Lez-T Letrozole 2.5 mg Tablets

Lez-T Letrozole 3×10 Tablets 2.5mg:

Lez-T Letrozole Tablets Composition:

Active ingredient:

Each film-coated tablet contains:

Letrozole 2.5mg (USP Specs)

Price: 6000.00

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Inactive ingredients and allergens:

See section “6” For further information:

Read this package insert carefully in its entirety before using this medicine. This leaflet contains concise information about medicine. If you have further questions, refer to the doctor or pharmacist.

This medicine has been prescribed for the treatment of your ailment. Do not pass it on to others. It may harm them even if it seems to you that their ailment is similar.

This medicine is not intended for children and adolescents under 18 years of age.

1- What is The Medicine Intended For?

Adjuvant treatment of early-stage breast cancer in postmenopausal women. Extended adjuvant treatment of early-stage breast cancer in postmenopausal women following standard adjuvant tamoxifen therapy.

Treatment of advanced or metastatic breast cancer in postmenopausal women.

Treatment of advanced breast cancer in postmenopausal women with disease progression following treatment with antioestrogens.

Therapeutic group: Aromatase inhibitors (antiestrogens).

This medicine is a hormonal (or “endocrine”) breast cancer treatment. The growth of breast cancer is frequently stimulated by estrogens, which are female sex hormones. Lez-T reduces the amount of estrogen by blocking an enzyme (“aromatase”) involved in the production of estrogens and may therefore block the growth of breast cancers that need estrogen to grow. As a consequence, tumor cells slow down or stop growing and/or spreading to other parts of the body.

If you have any questions about how Lez-T works or why it has been prescribed for you, ask your doctor.

2- Before Using The Medicine Lez-T Letrozole

Follow all the doctor’s instructions carefully. They may differ from the general information in this article.

“Do not use the Lez-T Letrozole medicine if”

• You are allergic (hypersensitive) to letrozole or to any of the other ingredients contained in the medicine (listed in section 6 “Further Information” in this article. If you think you may be allergic, please refer to your attending doctor for advice.
• You still have menstrual periods, i.e., if you have not yet gone through menopause.
• You are pregnant.
• You are breastfeeding.

If any of these conditions apply to you, do not take this medicine and talk to your doctor.”

Special warnings regarding the use of the Lez-T Letrozole medicine:

Talk to your doctor or pharmacist before taking Lez-T if:

• You have severe kidney disease.
• You have severe liver disease.
• You have a history of osteoporosis or bone fractures.

If any of these conditions apply to you, tell your doctor.

Your doctor will take this information into account during your treatment with Lez-T.

If you are taking, or have recently taken, other medicines, including non-prescription medicines and food supplements inform the doctor or pharmacist.

Especially if you are taking:

• tamoxifen.
• Treatments that contain other antioestrogens or estrogens.
• Phenytoin.
• Clopidorgel.

Use of Lez-T and Food:

The tablet can be taken with or without food.

Elderly people (65 years of age and above)

Patients 65 years of age and over can use Lez-T at the same dosage as other adults.

Pregnancy, breastfeeding, and fertility

• You should only take Lez-T if you have gone through menopause. However, your doctor should discuss with you the use of effective contraception, as you may still have the potential to become pregnant during treatment with Lez-T.
• You must not take Lez-T if you are pregnant or breastfeeding, as it may harm your baby.

Driving and use of medicines:

If you feel dizzy, tired, drowsy, or generally unwell, do not drive or operate any tool/machines until you feel that these effects have passed.

Important information reading some of the ingredients of the medicine:

Lez-T contains lactose (milk sugar). If you have been told by your doctor that you have an intolerance to certain sugars, contact your doctor before taking this medicine.

3- How Should We Use Medicine?

Always use according to the doctor’s instructions. Check with your doctor or pharmacist if you are not sure.

Dosage and frequency of administration:

The dosage and treatment regimen will be determined by the doctor only. The usual dosage is generally one tablet of Lez-T once a day. Do not exceed the recommended dose.

Who to take Lez-T?

Taking Lez-T at the same time each day will help you remember when to take your tablet.

How to take Lez-T?

Swallow the tablet whole with a glass of water or other liquid.

Duration of treatment with Lez-T

Continue taking Lez-T every day for as long as your doctor tells you. You may need to take the medicine for months or even years. If you have any questions about how long to keep taking Lez-T, talk to your doctor.

Tests and followup

You should only take Lez-T under strict medical supervision. Your doctor will regularly monitor your condition to check whether the treatment is having the right effect.

Lez-T may cause thinning or wasting of your bones (osteoporosis) due to the reduction of estrogens in your body. Your doctor may decide to measure your bone density (a way of monitoring for osteoporosis) before, during the after treatment.

If you accidentally take a higher dosage

If you look at an overdose or if a child, or anymore else, has accidentally swallowed the medicine, immediately refer to the doctor or proceed to a hospital emergency room and bring the medicine package with you. Medical treatment may be necessary.

If you forgot to take the medicine

• If it is almost time for your next dose (i.e., within 2 or 3 hours), skip the dose you missed and take your next dose at the regular time.
• Otherwise, take the dose as soon as you remember, and then take the next tablet as you would normally.
• Do not take a double dose to make up for the one that you missed.

Adhere to the treatment as recommended by the doctor.

If you stop taking Lez-T

Even if there is an improvement in your health, do not stop treatment with the medicine without consulting the doctor. See also “Duration of treatment with Lez-T above.

Do not take medicine in the dark! Check the label and the dose each time you take medicine. Wear glasses if you need them. If you have further questions regarding the use of this medicine, consult the doctor or pharmacist.

4- Side Effects

As with any medicine, the use of Lez-T may cause side effects in some users. Don not be alarmed when reading the list of side effects. You may not suffer from any of them. Most of the side effects are mild to moderate and will generally disappear after a few days to a few weeks of treatment. Some of the side effects, such as hot flushes, hair loss, or vaginal bleeding may be due to the lack of estrogens in your body.

Side Effects That May Be Severe:

Refer to a doctor immediately if you suffer any of the following conditions:

Rare or uncommon side effects (effects that may affect between 1 to 100 in every 10,000 patients):

• Weakness, paralysis, or loss of feeling in any part of the body (particularly arm or leg), loss of coordination, nausea, or difficulty speaking or breathing (a sign of a brain disorder, e.g., stroke).
• Sudden oppressive chest pain (the sign of a heart disorder).
• Difficulty breathing, chest pain, fainting, rapid heart rate, bluish skin discoloration, or sudden arm, leg, or foot pain (the sign that a blood clot may have formed).
• Selling and redness along a vein that is extremely tender and possibly painful when touched.
• Severe fever, chills, or mouth ulcers due to infections (lack of white blood cells).
• Severe persistent blurred vision.

You should also inform the doctor immediately if you suffer from any or of the following symptoms during treatment with Lez-T.

• Swelling mainly of the face and throat (signs of allergic reaction).
• Yellow skin and eyes, nausea, loss of appetite, dark-colored urine (the sign of hepatitis).
• Rash, red skin, blistering of the lips eyes, or mouth, skin peeling, fever (signs of skin disorder).

Additional side effects:

Very common side effects-effects that may affect more than 10 in every 100 patients: Hot lushes; high level of cholesterol (hypercholesterolemia); fatigue (including weakness generally feeding unwell: increased sweating; pain in bones and joints (arthralgia).

If one or more of these effects affect you weekly, refer to your doctor.

Common side effects-effects that may affect between 1 to 10 in every 100 patients: Skin rash; headache; dizziness, gastrointestinal disorders such as nausea, vomiting, indigestion, constipation, diarrhea, increase in or loss of appetite; pain in muscles, thinning or wasting of you bones (osteoporosis), leading to bone fractures in some cases (see “Test and follow-up” in section 3); swelling of arms, hands, feet, and ankles (edema); depression; weight increase, hair loss; raised blood pressure (hypertension); abdominal pain; dry skin; vaginal bleeding.

If one or more of these effects affect you severely, refer to your doctor.

Uncommon side effects-effects that may affect between 1 to 10 in every 1,000 patients: Nervous system disorders such as anxiety, nervousness, irritability, drowsiness, memory problems, somnolence, insomnia, pain or burning sensation in the hands or wist (capital tunnel syndrome); impairment of sensation, especially that of touch; eye disorders such as blurred vision, eye irritation, palpitations, rapid heart rate, skin disorder such as itching (urticaria), vaginal discharge or dryness; joint stiffness (arthritis); breast pain; fever; thirst, taste disorder, dry mouth; dryness of mucous membranes; weight decrease; urinary tract infection, increased frequency of urination, cough, increased level of enzymes.

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Side effects with frequency not known: Trigger finger, a condition in which your finger or thumb catches in a bent position.

If one or more of these effects affect you severely refer to your doctor.

If any of the side effects women or if you suffer from a side effect not mentioned in the leaflet you should consult your doctor.

5- How should the medicine be stored?

• Avoid poisoning. This medicine and any other medicine must be kept in a closed place out of the reach and sight of children and/or infants to avoid poisoning. Do not induce vomiting unless clarified indicated by the doctor.
• Do not use the medicine after the expiry date (exp. date) appearing on the package. The expiry date refers to the last day of that month.
• Do not store at a temperature exceeding 30 C.
• Sore in the original package to protect the tablets from moisture.
• Do not use if the package is damaged or has signs of tampering.

6- Ruther Information

Lez-T is available in a pack of 30 Tablets.